Nasolabial folds are the creases that run from the nose to the mouth corners. They become more prominent with age as midface fat pads descend, skin loses elasticity, and repeated facial expressions etch the fold more deeply.

First-line care typically uses dermal fillers (Juvéderm, Restylane, RHA, Radiesse) to restore midface support and soften the fold. Biostimulatory options such as Sculptra or Ariessence Pure PDGF+ help stimulate collagen for longer-lasting improvement.

Adults with moderate-to-deep smile lines seeking natural softening without surgery.