Lip lines form from repetitive orbicularis oris muscle activity (pursing, sipping, smoking), coupled with age-related collagen loss and skin thinning. Sun exposure, smoking, and genetics can make them appear earlier or more pronounced.

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First-line care often combines conservative neuromodulator micro-doses to soften muscle pull with hyaluronic acid fillers (Restylane, RHA, Juvéderm) to smooth etched-in lines. Supportive options include microneedling, RF microneedling, and chemical peels to rebuild collagen and refine skin texture.

Adults with fine-to-moderate perioral lines seeking natural smoothing and lip definition.